This product is supplied as a pure compound for research purposes only and is not intended for use as a dietary supplement, drug, or consumer product. Please refer to our Terms & Conditions prior to purchase.
TB-500 is a synthetic peptide derived from thymosin beta-4, studied for its ability to promote cell migration, reduce inflammation, and enhance tissue repair in non-human test subjects, making it a valuable tool in regenerative research applications.
TB-500 – Thymosin Beta-4 Fragment
TB-500 is a synthetic peptide modeled after a segment of thymosin beta-4, a naturally occurring protein associated with cellular repair and regeneration. In controlled laboratory settings, TB-500 is studied for its ability to support tissue recovery, cellular migration, and structural remodeling in non-human test subjects.
The peptide’s key mechanism involves actin binding and regulation, a process fundamental to cell structure and motility. By promoting actin organization, TB-500 enhances cell migration and differentiation, processes that are essential to wound healing and tissue regeneration.
Research indicates that TB-500 may facilitate angiogenesis (new blood vessel formation), inflammation modulation through cytokine balance, and oxidative stress reduction by influencing reactive oxygen species (ROS) activity. These properties have made it a valuable model compound for studying repair mechanisms in muscle, tendon, epithelial, and cardiovascular tissues.
Its low molecular weight and distinctive amino acid sequence enable systemic distribution and targeted activity at sites of injury or inflammation. TB-500’s multifunctional role in promoting regenerative pathways continues to make it a cornerstone molecule in advanced biochemical and tissue-repair research.
Summary of Characteristics
| Characteristic | Details |
|---|---|
| Chemical Sequence (Amino Acids) | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH |
| CAS Number | 77591-33-4 |
| Molecular Formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| Molecular Weight | 4963.49 g/mol |
| Other Known Titles | Thymosin Beta-4 Fragment; TB-500; TB-4 Acetate |







